Moorestown, New Jersey, United States
novel coronavirus (2019-nCoV) 病毒：新型冠状病毒 2019-nCoV
Dr Norman Swan discusses Germany's concerns around the AstraZeneca vaccine in the elderly | ABC News
•Jan 28, 2021 ABC News (Australia) ABC News (Australia)
America has done so little of the genetic sequencing needed to detect mutated versions of coronavirus, like those first discovered in Britain and South Africa, that such variants are likely proliferating quickly, undetected, experts said. By William Wan and Ben Guarino
New Playbook for Covid-19 Protection Emerges After Year of Study, Missteps
Mask-wearing, good air flow and frequent rapid tests are more important than surface cleaning, temperature checks and plexiglass. Scientists say America needs to double down on protection protocols as potentially more-contagious coronavirus variants take hold and vaccines are slow to roll out.
New coronavirus variants — and more yet to come — will challenge existing vaccines’ effectiveness and require the continual production of new versions of vaccine directed at specific mutations, said Anthony S. Fauci, the top U.S. infectious-disease expert.By Erin Cunningham, Kim Bellware, Dan Diamond and Amanda Coletta
Coronavirus: new clinical trials raise fears the virus is learning how to resist vaccines
Laboratory tests had suggested that the vaccines authorized in the US trigger a smaller immune response to the South Africa variant
More than 100 million people have been infected worldwide, and each of those infections is an opportunity for the virus to randomly mutate
Associated Press Published: 5:10am, 31 Jan, 2021
Latest Covid Surge Appears to Flame Out Even in Worst Hot Spots
Covid Mutations Undercut Optimism Even as More Vaccines Get Near
J&J Single-Dose Vaccine Is 100% Effective at Preventing Deaths, Hospital Stays
U.S. Tests More for Variants; NYC to Ease Dining: Virus Update
Tallying Countries Vaccine Contracts: Covid-19 Deals Tracker
J&J’s Vaccine Results Are In. So What’s the Verdict?
Moderna asks FDA to authorize 5 additional doses per Covid vaccine vial to speed distribution, source tells CNBC
PUBLISHED FRI, JAN 29 20216:27 PM ESTUPDATED FRI, JAN 29 20218:20 PM EST Meg Tirrell KEY POINTS
- Moderna is said to have asked the FDA to allow it to put additional doses in its vaccine vials.
- The move is aimed at alleviating a bottleneck in Covid-19 vaccine manufacturing.
- The change would add up to five doses to the 10-dose vials.
Lionel Laurent
- Vaccine development exceeded everyone’s expectations. But the next few months will still bring many sick people — with few drugs to treat them.
- Many promising drugs that could stop the disease early, called antivirals, have been neglected in the rush to develop vaccines.
Wait times for elective surgery in Tasmania on the rise | ABC News
Jan 28, 2021 ABC News (Australia) ABC News (Australia)
The more virulent strain first found in South Africa presents a serious test to efforts to tame the pandemic, prompting governments to swiftly tighten borders.
The first American evacuees from China were met last year by U.S. officials with no virus-prevention plan or infection control training, according to a federal investigation. By Dan Diamond
Pfizer, BioNTech Covid Vaccine Safe for the Elderly, EMA Says
World’s Most Vaccinated Nation Struggles With Virus Variants
#Gravitas #Astrazeneca #Europe
Gravitas: Europe's vaccine rollout disaster
•Jan 28, 2021 WION WION
JANUARY 28, 20217:54 AM
German expert panel recommends giving AstraZeneca shot only to under 65s
By Reuters Staff BERLIN, Jan 28 (Reuters)
Two people in South Carolina have been infected with the coronavirus variant, which has mutations that scientists say could allow the virus to elude some treatments and threaten vaccines’ effectiveness. Neither person had a recent history of travel.By Joel Achenbach and Carolyn Y. Johnson
J&J Covid Vaccine Supply to Start at 2 Million Doses, GAO Says
NYC Asks Government Workers to Return to Office in May
Novavax Soars After Upbeat Results From Covid Vaccine Trial
Ninety percent of new cases are of the variant, and excess mortality figures have spiked. By Lesley Wroughton and Max Bearak
- World caught in ‘pandemic paradox’ in race between new virus variants and distributing limited vaccines, says WHO official
- Tracking U.S. vaccinations by state
Novavax COVID-19 Vaccine Demonstrates 89.3% Efficacy in UK Phase 3 Trial
Jan 28, 2021 at 4:05 PM EST Download PDF
First to Demonstrate Clinical Efficacy Against COVID-19 and Both UK and South Africa Variants
- Strong efficacy in Phase 3 UK trial with over 50% of cases attributable to the now-predominant UK variant and the remainder attributable to COVID-19 virus
- Clinical efficacy demonstrated in Phase 2b South Africa trial with over 90% of sequenced cases attributable to prevalent South Africa escape variant
- Company to host investor conference call today at 4:30pm ET
GAITHERSBURG, Md., Jan. 28, 2021 (GLOBE NEWSWIRE) -- Novavax, Inc. (Nasdaq: NVAX), a biotechnology company developing next-generation vaccines for serious infectious diseases, today announced that NVX-CoV2373, its protein-based COVID-19 vaccine candidate, met the primary endpoint, with a vaccine efficacy of 89.3%, in its Phase 3 clinical trial conducted in the United Kingdom (UK). The study assessed efficacy during a period with high transmission and with a new UK variant strain of the virus emerging and circulating widely. It was conducted in partnership with the UK Government’s Vaccines Taskforce. Novavax also announced successful results of its Phase 2b study conducted in South Africa.
South African Covid Variant Detected for the First Time in U.S.
“It’s on me not because any brother or male relative refused to, but because I don’t think it occurred to them,” one Virginia woman said. By Soo Youn
How will the government react to an expose? By Steven Zeitchik
- Novavax’s vaccine works well, except on the variant first found in South Africa.
- The variant that emerged in South Africa is reported in the U.S. for the first time.
#WorldNewsTonight #PresidentJoeBiden #COVID19
Nationwide vaccine shortage as COVID-19 variant confirmed in half the country
•Jan 27, 2021 ABC News ABC News
The road to eliminating Covid-19 is long and paved with uncertainty.
Coronavirus: Cambodian scientists find close match for pathogen in samples collected in 2010
Viral sequences in samples from horseshoe bats have 92 per cent similarity to Covid-19 pathogen, researchers say
Closest known relative to the coronavirus was a bat virus found in Yunnan province, which is a 96 per cent match
Simone McCarthy Published: 12:00pm, 28 Jan, 2021
“Let’s not wait until we wrap the car around the tree to start pumping the brakes.”
Stanley Plotkin, legendary vaccinologist, on the historic development and chaotic distribution of covid-19 vaccinesAs told to Eli Saslow
By Terrence McCoy and Heloísa Traiano
Top administration officials launched regular briefings on their coronavirus response by seeking to illustrate their fidelity to science and transparency.
By Amy Goldstein and Lena H. Sun
EU's Vestager Says Astra Vaccine Delay Not About Bureaucracy
•Jan 27, 2021 Bloomberg Markets and Finance Bloomberg Markets and Finance
AstraZeneca and EU at loggerheads over COVID-19 vaccine supplies
Jan. 27, 2021 4:02 PM ET AstraZeneca PLC (AZN) By: Dulan Lokuwithana, SA News Editor
- Tensions keep rising between British drug developer AstraZeneca (NASDAQ:AZN) and the European Union over the supply delays for the company’s coronavirus vaccine co-developed with the University of Oxford.
- The 27-member bloc is far behind in the COVID-19 vaccination drive, with just over 2% of the region’s populations receiving at least one dose compared to over 40% in Israel and 10% in Britain.
https://seekingalpha.com/news/3655144-astrazeneca-and-eu-at-loggerheads-over-covid-19-vaccine-supplies
By RAF CASERT, SAMUEL PETREQUIN and DANICA KIRKA
By Erin Cunningham, Paul Schemm, Loveday Morris and Marisa Iati
- Biden administration seeks to buy 200 million more vaccine doses, to be delivered through the summer
- Tracking U.S. vaccinations by state
Biden officials set out another target for vaccination.
More contagious virus variants have spread to dozens of countries, says WHO
Coronavirus: more contagious variants have spread to dozens of countries, says WHO
The strain first spotted in Britain has reached 70 countries, while the one first found in South Africa has spread to 31 countries A third variant, discovered in Brazil, is now in eight countries
Agence France-Presse Published: 1:54am, 28 Jan, 2021
Moderna Confirms Discussions with U.S. Government for Additional 100 Million Doses of the Moderna COVID-19 Vaccine
January 27, 2021 at 8:20 AM ESTPDF Version
Would bring total to 300 million doses ordered by the U.S government to date
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Jan. 27, 2021-- Moderna, Inc. (Nasdaq: MRNA), a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines today confirmed that the Company is in discussion with the U.S. government to purchase an additional 100 million doses of the Moderna COVID-19 Vaccine for delivery in the third quarter of 2021.
By ZEKE MILLER and RICARDO ALONSO-ZALDIVAR
Full Coverage: Coronavirus pandemic
Tracking Covid-19 Hospitalizations in the U.S.
The number of coronavirus cases in the U.S. is surging, and along with that are the number of hospitalizations. Track the number of hospitalizations by state.
The Latest: FEMA to reimburse states for some pandemic costs
SHAREMONDAY, JANUARY 25, 2021 | THE ASSOCIATED PRESS
#Coronavirus #AstraZenica #Vaccine
Did AstraZeneca mislead the European Union? | DW News
•Jan 27, 2021 DW News DW News
It’s unclear whether increasing U.S. vaccine numbers will help return schools to in-person learning. A CDC report said that schools haven't been a major center of transmission.By Erin Cunningham and Paul Schemm
January 27 2021
Sanofi to provide support to BioNTech in manufacturing their COVID-19 vaccine to help address public health needs
Sanofi to provide support to BioNTech in manufacturing their COVID-19 vaccine to help address public health needs
- Sanofi will provide BioNTech access to its state-of-the-art production infrastructure
- From summer 2021, Sanofi will perform late-stage manufacturing to supply over 125 million doses of COVID-19 vaccine for the European Union
- This agreement between the two Companies reflects the shared commitment to increase vaccine accessibility
MEDIA UPDATE - JANUARY 27, 2021
https://www.sanofi.com/en/media-room/press-releases/2021/2021-01-27-07-30-00
Pfizer-BioNTech to Make 125 Million New Vaccine Doses in First-Ever Licensing Deal
Sanofi to Make Millions of BioNTech-Pfizer Vaccine Doses
By Tim Loh January 27, 2021, 3:01 AM EST Updated on January 27, 2021, 5:15 AM EST
- Collaboration will help boost European Union’s vaccine supply
- Companies pledge more than 125 million doses of mRNA shot
EU-Astra Vaccine Dispute Descends Into Chaos Over Crunch Call
Share of Americans Who Want Covid Vaccine Growing, Poll Finds
Biden’s Moves to Boost Vaccine Supply Won’t Sate Soaring Demand
By Hannah Natanson, Donna St. George and Perry Stein
January 27, 2021 at 7:00 AM EST
REGEN-COV™ ANTIBODY COCKTAIL IS ACTIVE AGAINST SARS-COV-2 VARIANTS FIRST IDENTIFIED IN THE UK AND SOUTH AFRICA
TARRYTOWN, N.Y., Jan. 27, 2021 /PRNewswire/ --
Columbia University researchers and Regeneron have independently confirmed findings; data included in bioRxiv paper and submitted for peer-reviewed publication
RISK LEVELS
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You can also read county-specific guidance for activities to help lower your personal risk.
by Ellie Silverman, Ellie Rushing and Oona Goodin-Smith The city said the group failed to promptly disclose its switch to a for-profit business and its privacy policy outlined ways personal information given by residents could be sold.
by Jason Laughlin and Maddie Hanna
Springside Chestnut Hill Academy’s aborted effort to vaccinate its staff highlighted the confusion and potential for inequity surrounding the hopes for protection from COVID-19 for school personnel.
Covid Deaths Persist in U.S. Even as Cases Drop Everywhere
Nic Querolo
EU threatens to impose controls on Pfizer vaccine exports
•Jan 26, 2021 Channel 4 News Channel 4 News
New Jersey launched a vaccine hotline. Four hours later, 58,000 calls had flooded in.
NEW JERSEY
COVID-19 Information Hub
Call (General COVID-19 Questions): 2-1-1 (24/7)
Call (Medical COVID-19 Questions): 1-800-962-1253Medical Information from healthcare professionals on symptoms, when to seek medical attention, and proper steps to take if exposed to COVID-19. (24/7)
Call (Vaccine Appointment Support): 1-855-568-0545 (8a-8p)
Text NJCOVID to 898-211 to receive alerts
Download COVID Alert NJ app here
Global Cases Top 100 Million; N.J. May Relax Curbs: Virus Update
Bloomberg NewsJanuary 25, 2021, 6:16 PM EST Updated on January 26, 2021, 4:46 PM EST
As the number of people who died reaches six figures, the factors that led to this terrible total. HEALTH
Some indoor athletics, however, have led to infections and should be curtailed if schools want to operate safely, researchers from the Centers for Disease Control and Prevention concluded in newly published papers. By Laura Meckler
JANUARY 26, 202112:29 PMUPDATED 3 HOURS AGO
Sanofi to help produce 100 million Pfizer/BioNTech vaccine doses
By Reuters Staff PARIS (Reuters)
Pfizer/ BioNTech to speed up COVID-19 vaccine supply
Jan. 26, 2021 9:28 AM ET Pfizer Inc. (PFE) By: Dulan Lokuwithana, SA News Editor12 Comments
https://seekingalpha.com/news/3654371-pfizer-biontech-to-speed-up-covid-19-vaccine-supply
It will increase the vaccine supply by 20%, Mr. Bourla had said previously, and the FDA issued a label change in that regard last week.
https://twitter.com/BloombergLive/status/1354062624049274885?s=20&source=content_type%3Areact%7Cfirst_level_url%3Anews%7Csection%3Amain_content%7Cbutton%3Abody_link
By William Booth and Karla Adam
Darden Offers Paid Time Off for Employees to Get Covid Vaccine
The Pandemic Disaster That Might Not Matter
- TOM MCTAGUE 1:00 AM ET
by Rob Tornoe, Laura McCrystal, Erin McCarthy and Robert Moran
The pandemic is softening, but the reprieve may not last.
Covid-19: Vaccine minister 'confident' of supplies 🔴 @BBC News live - BBC
Jan 26, 20212
Pfizer to Deliver U.S. Vaccine Doses Faster Than Expected: CEO
By Riley Griffin January 26, 2021, 8:51 AM EST
New data show treatment with Lilly's neutralizing antibodies bamlanivimab (LY-CoV555) and etesevimab (LY-CoV016) together reduced risk of COVID-19 hospitalizations and death by 70 percent
January 26, 2021Download PDF- BLAZE-1 trial met primary endpoint and key secondary endpoints with high statistical significance
- Results from more than 1,000 high-risk patients were consistent with previous data
- Findings from BLAZE-4 trial provide data on lower doses of bamlanivimab and etesevimab together
- Media and investor call "SARS-CoV-2 Neutralizing Antibody Program Update" to be held at noon EST today; details below
INDIANAPOLIS, Jan. 26, 2021 /PRNewswire/ -- Bamlanivimab (LY-CoV555) 2800 mg and etesevimab (LY-CoV016) 2800 mg together significantly reduced COVID-19-related hospitalizations and deaths (collectively, "events") in high-risk patients recently diagnosed with COVID-19, meeting the primary endpoint of the Phase 3 BLAZE-1 trial, Eli Lilly and Company (NYSE: LLY) announced. Across 1,035 patients, there were 11 events (2.1 percent) in patients taking therapy and 36 events (7.0 percent) in patients taking placebo, representing a 70 percent risk reduction (p= 0.0004). There were 10 deaths total, all of which occurred in patients taking placebo, and no deaths in patients taking bamlanivimab and etesevimab together.
Eli Lilly (LLY -0.02%) reports new data from Phase 3 Blaze-1 trial, evaluating bamlanivimab and etesevimab antibody combination in critically-ill COVID-19 patients.
A Study of LY3819253 (LY-CoV555) and LY3832479 (LY-CoV016) in Participants With Mild to Moderate COVID-19 Illness (BLAZE-1)
https://clinicaltrials.gov/ct2/show/NCT04427501
Can India outshine China with Covid-19 vaccine diplomacy?
India is donating millions of AstraZeneca shots to countries including Bangladesh, Sri Lanka, Nepal and Mauritius
New Delhi says 92 nations including Cambodia, a close ally of Beijing, are interested in vaccines produced by the Serum Institute of India
Subir Bhaumik Published: 12:05pm, 26 Jan, 2021
On Monday, President Biden said he could envision 1.5 million U.S. vaccinations per day. The recalibration reflects the reality that the country is already close to the million-a-day pace. By Annie Linskey
More than 100 positive cases have been identified in the city of Harbin, all of which are thought to be linked to a local food production subsidiary of CP Group
Jan 26, 2021 07:24 PM
Explainer | How the Covid-19 vaccines compare and who can get them
The race to carry out the biggest inoculation programme in history has begun, with six products approved and more to follow.
Indonesia hits 1 million cases; Australians defy Covid-19 curbs
Elsewhere, New Zealand is closing in on approving a Covid-19 vaccine, and the Serum Institute of India says it has no plans to divert vaccine supplies to Europe despite production problems there.
Moderna says vaccine works against new Covid-19 variants
Lab tests show shot produces comparable antibody protection against UK strain, but immunity may wane more quickly for South Africa variant.
26 Jan 2021 - 2:00PM
STOPPING THE NEXT ONE | INFECTIOUS DISEASE
The coronavirus 10 times more deadly than Covid
By Jacob Kushner in Marsabit, Kenya 25th January 2021
In northern Kenya, researchers are working to prevent a dangerous coronavirus – Mers – from jumping from camels to humans again. But climate change is making their job more difficult.
https://www.bbc.com/future/article/20210122-the-coronavirus-10-times-more-deadly-than-covid
Florida tightens Covid-19 vaccination requirements across the state
•Jan 25, 2021 CNBC Television CNBC Television
Life after the COVID-19 vaccine: Americans won’t rush back to restaurants and ballgames — or public transportation
Last Updated: Jan. 25, 2021 at 6:16 p.m. ET First Published: Jan. 25, 2021 at 11:07 a.m. ET
‘The arrival of vaccines won’t automatically flip a switch to put the world back on its pre-COVID path,’ said Scott McKenzie, global intelligence leader at Nielsen
Coronavirus: Germany to use new antibody-based drug
Health Minister Jens Spahn has said the government has purchased a new drug to help fight COVID-19 amid a vaccine shortage. Germany will be the first EU nation to use the medicine, which was also given to Donald Trump.
Developing our Novel Anti-Viral Antibody Cocktail
Casirivimab and imdevimab form a novel monoclonal antibody cocktail being studied for its potential both to treat appropriate patients with COVID-19 and to prevent SARS-CoV-2 infection.
Casirivimab and imdevimab are investigational therapies and have been authorized by the FDA for the emergency use described below. Casirivimab and imdevimab must be administered together. Casirivimab and imdevimab are not FDA approved for any use. Safety and effectiveness of casirivimab and imdevimab have not been fully established for the treatment of COVID-19.
https://www.regeneron.com/covid19
State health authorities said the case of the highly transmissible variant involved “a Minnesota resident with recent travel history to Brazil” and was detected through random surveillance of blood samples. By Joel Achenbach
N.Y. to Start Easing Curbs; Dutch Riot Over Curfew: Virus Update
Florida’s resident death toll from coronavirus rose to 25,446 with the addition of 153 more reported fatalities on Monday while also adding 8,720 more positive COVID-19 cases to bring the total to 1,658,169.By RICHARD TRIBOU
- The company’s vaccine produces fewer protective antibodies against the variant found in South Africa, so it is working on a new version.
- Merck said it was abandoning a pair of vaccines in clinical trials after disappointing results.
- California has lifted severe coronavirus restrictions in huge swaths of the state, home to tens of millions of people. Here’s the latest.
Fauci Says He’s Worried About Delaying Second Vaccine Dose
Thomas Mulier and Corinne Gretler
New coronavirus variants are an urgent threat. Here’s what you need to know
Skelton: It shouldn’t be this hard getting COVID-19 vaccine into people’s arms
URI FRIEDMAN JANUARY 23, 2021
Google to invest millions in coronavirus vaccine education and access
Coronavirus crisis: Vaccine rollout grows amid travel ban and variant concerns
•Jan 25, 2021 ABC News ABC News
Jan 25, 2021 07:57 PM CHINA
Leading Chinese Drug Researcher Calls for Greater Transparency on China Vaccines
By Wang Lijun, Wang Zhuoqing and Timmy Shen
JANUARY 25, 202110:13 AM UPDATED 3 HOURS AGO
Exclusive: Pfizer wants India to order COVID-19 vaccine before pursuing approval
By Krishna N. Das NEW DELHI (Reuters)
- President Biden plans to bar travel by noncitizens into the U.S. from South Africa amid concerns over the coronavirus variants, a White House official said.
- Prime Minister Boris Johnson of Britain is expected to tighten lockdown rules, including keeping schools closed until April. Here’s the latest pandemic news.
“We’re not going to be able to soar until we get more supply,” Mayor de Blasio says.
Even under the most optimistic assumptions, working hours will still be lower compared to pre-crisis levels.
By Teo Armus
Moderna said its Covid-19 vaccine appeared to protect against emerging strains in lab tests, but due to a weaker immune response, the company will develop a booster shot targeting the variant first identified in South Africa.
Coronavirus: EU locks horns with AstraZeneca on vaccine deliveries amid ‘supply shock’
The drug maker is struggling to meet supply targets up to the end of March
Australia and Thailand are among countries that face supply cuts, with the latter to get some 150,000 doses instead of the 1 million it had initially requested
Reuters Published: 11:52pm, 25 Jan, 2021
As Covid-19 cases increase sharply in much of the world, a scarcity of oxygen is forcing hospitals to ration it for patients. The problem is especially acute in the developing world, but has also hit hospitals in London and Los Angeles.
Covid-19 Vaccine: What You Need to Know When You Get the Shot
Doctors answer questions about preparing for the Covid-19 vaccine
By Alina Dizik Updated Jan. 23, 2021 4:01 pm ET
Why Delaying the Second Covid Vaccine Shot Is Messy
John Lauerman and Jason Gale 1/25/21, 2:43 AM EST
A Guide to the New Covid-19 Testing Rules for Travel to the U.S.
The CDC will require preflight testing as Covid-19 cases continue to soar and new strains of the virus emerge
By Alison Sider Updated Jan. 22, 2021 2:59 pm ET
U.S. to Boost Surveillance of Virus Variants, CDC Head Says
Tony Czuczka and Craig Torres 1/24/21, 1:15 PM EST
#nanographics #visualization #biology
What does a virus actually look like?
1Jan 18, 2021 Too Dope for Microscope
Real SARS-CoV-2 virion in 3D
What does a virus actually look like?
This is the first time you can see real (flash-frozen) coronavirus in 3D. We used machine learning and advanced visualization algorithms to show you the most detailed view of a real SARS-CoV-2 virion, in 3D, directly from Cryo-ET data.
https://nanographics.at/projects/coronavirus-3d/
https://nanographics.at/
The Cryo-ET data were provided by Sai Li of Tsinghua University, Beijing, China.
https://www.tsinghua.edu.cn/en/index.htm
The structure of the novel coronavirus SARS-CoV-2
•Apr 30, 2020
https://www.youtube.com/watch?v=IB3ujgoniVQ&feature=emb_logo
Coronavirus SARS-CoV-2
https://nanographics.at/projects/sars-cov-2/
First 3D scan of the real coronavirus revealed
•Jan 25, 2021
South China Morning Post South China Morning Post
Real SARS-CoV-2 virion in 3D
What does a virus actually look like?
This is the first time you can see real (flash-frozen) coronavirus in 3D. We used machine learning and advanced visualization algorithms to show you the most detailed view of a real SARS-CoV-2 virion, in 3D, directly from Cryo-ET data.
https://nanographics.at/projects/coronavirus-3d/
https://nanographics.at/
The Cryo-ET data were provided by Sai Li of Tsinghua University, Beijing, China.
https://www.tsinghua.edu.cn/en/index.htm
Covid-19 pandemic: in-depth analysis one year after Wuhan
Updated: 15 Jan 2021