Moorestown, New Jersey, United States
BiotechSTORM™ novel coronavirus (2019-nCoV)/Monkeypox/Polio
China’s Top Virologist Issues STARK WARNING That Another Coronavirus Outbreak Highly Likely: Report
The Hill WASHINGTON 9/28/2023
Briahna Joy Gray and Amber Athey react to a new research paper authored by one of China's top virologists that another coronavirus outbreak is very likely. #covid19 #coronavirus
Open Access Published: 28 September 2023
SARS-CoV-2 infection triggers pro-atherogenic inflammatory responses in human coronary vessels
- Natalia Eberhardt, Maria Gabriela Noval, Ravneet Kaur, Letizia Amadori, Michael Gildea, Swathy Sajja, Dayasagar Das,
- Burak Cilhoroz, O’ Jay Stewart, Dawn M. Fernandez, Roza Shamailova, Andrea Vasquez Guillen, Sonia Jangra,
- Michael Schotsaert, Jonathan D. Newman, Peter Faries, Thomas Maldonado, Caron Rockman, Amy Rapkiewicz,
- Kenneth A. Stapleford, Navneet Narula, Kathryn J. Moore & Chiara Giannarelli
Nature Cardiovascular Research (2023)Cite this article
- 1182 Altmetric Metricsdetails
Abstract
Patients with coronavirus disease 2019 (COVID-19) present increased risk for ischemic cardiovascular complications up to 1 year after infection. Although the systemic inflammatory response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection likely contributes to this increased cardiovascular risk, whether SARS-CoV-2 directly infects the coronary vasculature and attendant atherosclerotic plaques remains unknown. Here we report that SARS-CoV-2 viral RNA is detectable and replicates in coronary lesions taken at autopsy from severe COVID-19 cases. SARS-CoV-2 targeted plaque macrophages and exhibited a stronger tropism for arterial lesions than adjacent perivascular fat, correlating with macrophage infiltration levels. SARS-CoV-2 entry was increased in cholesterol-loaded primary macrophages and dependent, in part, on neuropilin-1. SARS-CoV-2 induced a robust inflammatory response in cultured macrophages and human atherosclerotic vascular explants with secretion of cytokines known to trigger cardiovascular events. Our data establish that SARS-CoV-2 infects coronary vessels, inducing plaque inflammation that could trigger acute cardiovascular complications and increase the long-term cardiovascular risk.
https://www.nature.com/articles/s44161-023-00336-5
September 27, 2023
Artificial-intelligence technology can guide surgeons, which should make complicated operations safer.
Many people are needlessly avoiding the most common antibiotics, which are the most effective.
The messaging around vaping may be driving children and teens to take up the habit, says expert.
Video footage shows the man removing full shopping bags and fleeing before police arrived.
The new drug MDR-001 could become a disruptor in treatment of obesity and diabetes.
Mainland social media has been moved by the story of a caring eight-year-old boy in China who used toy string to tie himself to his sister, 3, as they waited for their abused mother to have hospital check-up.
28 Sep 2023 - 6:10PM
Federal child-care funding is expiring, which may send providers spiraling. California will probably avoid the worst impact because of efforts to backfill funding.
Nearly 9 million Americans have long COVID, CDC says
CBS News Sep 27, 2023
Reports published Tuesday by the Centers for Disease Control and Prevention say nearly 18 million Americans experienced symptoms of long COVID — when symptoms remain for at least four weeks after a patient has cleared the infection — in 2022 and nearly 9 million people currently have the condition, which can linger for months or years. CBS News medical contributor Dr. Celine Gounder, editor-at-large for public health at KFF Health News, has more on the report's findings.
Lisa Jarvis | Columnist
Long Covid Is Real. Now the Evidence Is Piling Up.
CVS Faces Lawsuit from Local Pharmacy Alleging Unfair Fees for Dispensing Drugs
A child in Germany has received a gene-based therapy tailored to his gene defect – a first in Europe. September 21, 2023
Meet a young Nigerian who conquered her depression. September 20, 2023
BENJAMIN MAZER SEPTEMBER 27, 2023
It’s the Best Time in History to Have a Migraine
Covid may have permanently damaged people's immunity
Wed, Sep 13
Covid infections are putting people at higher risk of diabetes, strokes, heart disease and other long-term illnesses - but experts warn it may be decades before the full impact is known.
https://www.1news.co.nz/2023/09/13/covid-may-have-permanently-damaged-peoples-immunity/
Open Access Published: 27 September 2023
Duration of SARS-CoV-2 mRNA vaccine persistence and factors associated with cardiac involvement in recently vaccinated patients
npj Vaccines volume 8, Article number: 141 (2023) Cite this article 790 Altmetric Metricsdetails
Abstract
At the start of the COVID-19 pandemic, the BNT162b2 (BioNTech-Pfizer) and mRNA-1273 (Moderna) mRNA vaccines were expediently designed and mass produced. Both vaccines produce the full-length SARS-CoV-2 spike protein for gain of immunity and have greatly reduced mortality and morbidity from SARS-CoV-2 infection. The distribution and duration of SARS-CoV-2 mRNA vaccine persistence in human tissues is unclear. Here, we developed specific RT-qPCR-based assays to detect each mRNA vaccine and screened lymph nodes, liver, spleen, and myocardium from recently vaccinated deceased patients. Vaccine was detected in the axillary lymph nodes in the majority of patients dying within 30 days of vaccination, but not in patients dying more than 30 days from vaccination. Vaccine was not detected in the mediastinal lymph nodes, spleen, or liver. Vaccine was detected in the myocardium in a subset of patients vaccinated within 30 days of death. Cardiac ventricles in which vaccine was detected had healing myocardial injury at the time of vaccination and had more myocardial macrophages than the cardiac ventricles in which vaccine was not detected. These results suggest that SARS-CoV-2 mRNA vaccines routinely persist up to 30 days from vaccination and can be detected in the heart.
‘Clear differences' in blood of patients with long COVID, research shows
NBC Bay Area Sep 25, 2023
People who feel they may be suffering from the effects of what is known as “long COVID” now have a way to know for sure.
In 12-hour shifts at Temple University Hospital, Yalonda Fowler often takes care of five patients.
The pharmaceuticals sector is enduring a tough year in the stock market. Companies selling weight-loss drugs are a big exception.
China’s ‘batwoman’ scientist warns another coronavirus outbreak is ‘highly likely’
- Shi Zhengli and colleagues at the Wuhan Institute of Virology warn in a paper that there are 20 ‘highly risky’ coronavirus species
- One scientist compared the research to a ‘dictionary of coronaviruses’ that could prove to be a valuable guide in future
Dannie Peng Published: 9:05am, 24 Sep, 2023
The number of births in China halved in the six years to 2022 and will continue dropping without solutions to key problems like the decline in marriages and desire to have kids, says He Yafu
Sep 26, 2023 09:10 PM
Pandemic Spending Put Local Chinese Governments $548 Billion in the Red
In another attempt to settle a lawsuit, Los Angeles County has agreed to create 3,000 new mental health and substance use treatment beds by the end of 2026.
The booming popularity of countertops made of engineered stone has driven a new epidemic of silicosis, an incurable lung disease, researchers have found.
How federal missteps opened door to COVID misinformation
Liz Mineo Harvard Staff Writer DATE September 25, 2023
More than a decade after California passed the Human Right to Water Act, about 1 million residents still lack access to clean, safe, affordable water.
Highly mutated COVID-19 variant found in at least 10 states
CBS News Sep 19, 2023 #news #covid #covid19
A new and highly mutated strain of COVID-19 has been detected in at least ten states, but for now, the strain is rare, accounting for just a small fraction of new COVID cases nationwide. Dr. Bob Lahita, director of the Institute for Autoimmune and Rheumatic Diseases at Saint Joseph Health in Saddle River, New Jersey, joined CBS News to discuss the new variant. #news #covid #covid19
Pandemic Aid for Public Schools Is Running Out. That’s Leaving Districts Under Pressure
A cell therapy for multiple myeloma promises to be a major blockbuster for J&J and partner Legend, if they can increase manufacturing.
A child in Germany has received a gene-based therapy tailored to his gene defect – a first in Europe
Meet a young Nigerian who conquered her depression. September 20, 2023
September 19, 2023
September 19, 2023
Apart from the government, grassroots workers have been instrumental in improving child health. DW met one such worker. September 18, 2023
The climate crisis is being cited as a key factor in the country's worst-ever dengue outbreak. September 16, 2023
September 17, 2023
September 20, 2023
By Richard Sima
By Janet Lee
By Linda Searing
By Laurie McGinley and Daniel Gilbert
Why you might still have Covid-19 despite a negative test
As people are encouraged to get the new Covid-19 booster approved by the FDA and CDC, Dr. Saju Matthew explains why Covid-19 tests can sometimes return a fasle-positive and how to differentiate between Covid-19, the flu and RSV. #CNN #News
My husband has bone-marrow cancer. For us, the pandemic is only as over as it is safe to reenter the world: not particularly.Opinion by Esmé Weijun Wang
By Janet Lee
By Linda Searing
By Anumita Kaur
China beats US for first time in global scientific papers ranking
21 Sep 2023 - 2:00PM
HHS bars Wuhan Institute of Virology from receiving US funding for next 10 years: ‘Obvious step in the right direction’
By Josh Christenson Published Sep. 20, 2023, 6:46 p.m. ET
The Editorial Board
Here’s How Medicare Should Negotiate Drug Prices
AstraZeneca Sued by Staffer Whose Bonus Was Cut for Working at Home
It is increasingly clear to researchers that inflammation can raise the risk of a heart attack. Now doctors have a drug that addresses that risk.
Covid booster jabs for all
Dr. John Campbell Sep 15, 2023
Updated COVID-19 vaccines are recommended for everyone 6 months and older and will be available by the end of this week ‘Safe and effective’ Estimated hospitalizations prevented per 1,000,000 vaccine doses 12 -17 years 19-95 hospitalizations, 5-19 ICU admissions, and perhaps one death. 5 – 11 years 16 hospitalizations, (based on Spring 2023 data) 18 – 49 years 75 hospitalizations, (based on Spring 2023 data) Serious adverse events of special interest following mRNA COVID-19 vaccination in randomized trials in adults https://pubmed.ncbi.nlm.nih.gov/36055... Pfizer vaccines excess risk of serious adverse events (Higher than placebo baseline) 10.1 per 10,000 101 per 100,000 1,010 per 1,000,000 Moderna vaccines excess risk of serious adverse events (Higher than placebo baseline) 15.1 per 10,000 151 per 100,000 1,510 per 1,000,000 In Western Australia https://www.health.wa.gov.au/~/media/... Total AEFI rate following a COVID-19 vaccine 264.1 per 100,000 doses 2,641 per 1,000,000 doses https://www.reuters.com/business/heal... March 22 Moderna chief executive defended the company's plan to quadruple the price of its COVID-19 vaccine, $130 per dose Pfizer last year suggested $110 to $130 per dose. From FDA to MHRA: are drug regulators for hire? https://www.bmj.com/content/377/bmj.o... Money derived from Industry US Food and Drug Administration, $3,416,000,000 (2022) The revolving door FDA, nine out of 10 of its past commissioners, 2006 to 2019 went on to secure roles linked with pharmaceutical companies https://www.fda.gov/about-fda/fda-org... 2005 UK, House of Commons’ health committee Industry funding could lead MHRA, to “lose sight of the need to protect and promote public health above all else as it seeks to win fee income from the companies.” BMJ investigation (2022) We found that industry money permeates the globe’s leading regulators, raising questions about their independence Sociologist Donald Light, Rowan University, New Jersey “Like the FDA, the TGA was founded to be an independent institute. However, being largely funded by fees from the companies whose products it is charged to evaluate is a fundamental conflict of interest, and a prime example of institutional corruption.” It is no longer possible for doctors and patients to receive unbiased, rigorous evaluations from drug regulators. FDA “It’s the opposite of having a trustworthy organisation independently and rigorously assessing medicines. They’re not rigorous, they’re not independent, they are selective, and they withhold data. Doctors and patients must appreciate how deeply and extensively drug regulators can’t be trusted so long as they are captured by industry funding.” Revisiting financial conflicts of interest in FDA advisory committees https://pubmed.ncbi.nlm.nih.gov/25199... Large study, FDA advisory committee members over 15 years, those with financial interests solely in the sponsoring firm were more likely to vote in favour of the sponsor’s product.
Sore throat, then congestion: Common Covid symptoms follow a pattern now, doctors say
Doctors who treat Covid describe the ways the illness has gotten milder and shifted over time to mostly affect the upper respiratory tract.
Sept. 16, 2023, 8:00 AM EDTBy Aria Bendix
Doctors say they're finding it increasingly difficult to distinguish Covid from allergies or the common cold,
even as hospitalizations tick up.
September 16, 2023Health
Vaccine Injury Treatment - Fasting for 48-72 hours creates autophagy - the body's detox process that kills COVID-19 vaccine spike protein damaged cells and reboots the immune system
The benefits of fasting on COVID-19 vaccine injuries are now being looked at seriously in the scientific literature.ByInfluencers
Moderna CEO on New Flu Vaccine, Curing Cancer
Bloomberg Television Sep 13, 2023
Stephane Bancel, Moderna CEO, talks about seeking regulatory approval for a new version of its influenza vaccine, and new ways to treat and detect cancer. He speaks on "Bloomberg Markets."
The new COVID-19 vaccines for fall 2023 started rolling out this week. SEP 15
What is Nipah virus: Signs & sym ..
Updated: Sep 14, 2023, 09:08 IST
Read more at:
http://timesofindia.indiatimes.com/articleshow/103648803.cms?utm_source=contentofinterest&utm_medium=text&utm_campaign=cppst
The Kerala government has strengthened measures to prevent t ..
Read more at:
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https://timesofindia.indiatimes.com/city/kozhikode/what-is-nipah-virus/articleshow/103648803.cms
By Joel Zinberg | Commentary
Data increasingly suggest getting vaccinated reduces long COVID risk, a factor officials have cited in recommending most everyone get a reformulated vaccine this year.
A key unit at Santa Barbara Cottage Hospital has been restricted from accepting chronically ill children until it addresses state regulators’ concerns.
Covid, RSV and flu vaccines are now available — here’s how to decide whether to get them together
Study of cardiac arrest survivors reveals insight into near-death experiences
Over 700 people tested for Nipah virus after two deaths in India
Teddi Mellencamp reveals she has 'another melanoma' in emotional post
Fentanyl plus stimulants drives 'fourth wave' of overdose epidemic
Scientific study reveals more about life after death
What you need to know about the new Covid vaccine
A new study in Italy’s worst pandemic hot spot sheds light on why some people fell seriously ill—and others didn’t.
Moderna CEO: Covid is not going away
CNBC Television Sep 13, 2023 #CNBCTV #CNBC
Moderna CEO Stéphane Bancel joins 'Squawk Box' to discuss the company's new Covid-19 booster vaccine, their new products for cancer treatment, and more.
New Covid boosters could reach Americans as soon as Thursday – here’s what you need to know
Annika Kim Constantino WED, SEP 13TH 2023
Moderna says flu vaccine showed promising results, paving path to approval
Annika Kim Constantino WED, SEP 13TH 2023
CDC recommends updated Covid vaccines for everyone ages 6 months and up
Annika Kim Constantino TUE, SEP 12TH 2023
Decongestant found in popular cold, allergy medicines doesn’t work, FDA advisors say
Annika Kim Constantino TUE, SEP 12TH 2023
EMA Committee for Medicinal Products for Human Use Adopts Positive Opinion Recommending Authorization of Moderna’s Updated Covid-19 Vaccine in The European Union
14 September 2023
Moderna Expands the Field of mRNA Medicine with Positive Clinical Results Across Cancer, Rare Disease, and Infectious Disease
13 September 2023
Our Continued Innovation at Work: Celebrating U.S. FDA Approval of Our Updated COVID-19 Vaccine
11 September 2023
Moderna Receives U.S. FDA Approval for Updated COVID-19 Vaccine
11 September 2023
Moderna wins EU recommendation for updated COVID shot
Sep. 14, 2023 10:44 AM ET
By: Dulan Lokuwithana, SA News Editor1 Comment
- Moderna (NASDAQ:MRNA) announced Thursday that an expert panel of the EU drug regulator, the European Medicines Agency (EMA), adopted a positive opinion on its latest COVID-19 vaccine, recommending its marketing authorization for the region.
- https://seekingalpha.com/news/4011893-moderna-stock-up-eu-recommendation-updated-covid-shot
- Moderna, Inc. (MRNA)
- https://www.modernatx.com/
FDA approves updated Covid vaccines from Pfizer, Moderna MON, SEP 11TH 2023
HEALTH AND SCIENCE Covid vaccine rollout begins early in the UK with new variant under watch MON, SEP 11TH 2023
Ozempic, Wegovy may curb drinking, smoking, other addictive behaviors – what we know SUN, SEP 10TH 2023
The big obesity drug battle is just getting started, and headed for $100 billion SAT, SEP 9TH 2023
The company led by Joaquin Duato launches a rebranding as it focuses on higher-risk prescription drugs and medical devices after shedding its consumer business.
People more often are seeing test results before their doctors do.
CDC recommends updated COVID boosters aimed at new variants
CBS News Sep 12, 2023 #news #health #cdc
The CDC is recommending the new COVID booster shot universally for anyone older than 6 months after its panel of outside vaccine advisers endorsed it. Dr. William Schaffner, professor of infectious diseases at Vanderbilt University Medical Center, joined CBS News to talk about the new booster shots. #news #health #cdc
The Incidence of Myocarditis and Pericarditis in Post COVID-19 Unvaccinated Patients—A Large Population-Based Study Received: 25 March 2022 / Revised: 11 April 2022 / Accepted: 12 April 2022 / Published: 15 April 2022
https://www.mdpi.com/2077-0383/11/8/2219
Covid may have permanently damaged people's immunity
Wed, Sep 13
Covid infections are putting people at higher risk of diabetes, strokes, heart disease and other long-term illnesses - but experts warn it may be decades before the full impact is known.
https://www.1news.co.nz/2023/09/13/covid-may-have-permanently-damaged-peoples-immunity/
Environ Res. 2023 Jan 1; 216: 114655.
Published online 2022 Oct 28. doi: 10.1016/j.envres.2022.114655PMCID: PMC9613797PMID: 36341800
Age-stratified infection fatality rate of COVID-19 in the non-elderly population
Abstract
The largest burden of COVID-19 is carried by the elderly, and persons living in nursing homes are particularly vulnerable. However, 94% of the global population is younger than 70 years and 86% is younger than 60 years. The objective of this study was to accurately estimate the infection fatality rate (IFR) of COVID-19 among non-elderly people in the absence of vaccination or prior infection. In systematic searches in SeroTracker and PubMed (protocol: https://osf.io/xvupr), we identified 40 eligible national seroprevalence studies covering 38 countries with pre-vaccination seroprevalence data. For 29 countries (24 high-income, 5 others), publicly available age-stratified COVID-19 death data and age-stratified seroprevalence information were available and were included in the primary analysis. The IFRs had a median of 0.034% (interquartile range (IQR) 0.013–0.056%) for the 0–59 years old population, and 0.095% (IQR 0.036–0.119%) for the 0–69 years old. The median IFR was 0.0003% at 0–19 years, 0.002% at 20–29 years, 0.011% at 30–39 years, 0.035% at 40–49 years, 0.123% at 50–59 years, and 0.506% at 60–69 years. IFR increases approximately 4 times every 10 years. Including data from another 9 countries with imputed age distribution of COVID-19 deaths yielded median IFR of 0.025–0.032% for 0–59 years and 0.063–0.082% for 0–69 years. Meta-regression analyses also suggested global IFR of 0.03% and 0.07%, respectively in these age groups. The current analysis suggests a much lower pre-vaccination IFR in non-elderly populations than previously suggested. Large differences did exist between countries and may reflect differences in comorbidities and other factors. These estimates provide a baseline from which to fathom further IFR declines with the widespread use of vaccination, prior infections, and evolution of new variants.
https://ncbi.nlm.nih.gov/pmc/articles/PMC9613797/
Cyberbullies target overweight people, triggering further cravings. An influencer explains how to break the cycle. September 13, 2023
September 12, 2023
Jabs are being given faster than planned in England, with adults aged 65+ among those eligible.
Health officials say it is too early to know whether BA.2.86 is more serious than previous strains.
Shannon Meenan Browse died from malnutrition after gastric sleeve surgery in Turkey 18 months ago.
CDC director discusses updated COVID booster as infections rise from latest variant
PBS NewsHour Sep 12, 2023
A new round of COVID-19 boosters will be available within days as cases and hospitalizations continue to rise across the country. The Food and Drug Administration approved the new shots Monday and a CDC advisory panel recommended the updated boosters for all Americans 6 months or older. Amna Nawaz discussed the latest with CDC Director Dr. Mandy Cohen.
ADHD Drug Shortages Worsen as Makers Say Production Is Maxed Out
With supply constraints entering a second year, patients would like to see rules governing prescriptions loosened.
Americans can now get an updated COVID-19 vaccine.
Mike Stobbe and Lauran Neergaard, Associated Press
The AIDS Healthcare Foundation has been resisting a push from L.A. County to ask people if they have insurance that can cover costs for STD tests.
An agency whistle-blower claims CIA personnel were offered incentives to change their mind on the origin of the virus.
11 Sep 2023 - 4:17PM
Beigene,Ltd. Posted 2.4 Billion Yuan Net Loss in First Quarter of 2023 May 16, 2023 08:00 AM
Innocare Pharma Limited Posted 14.2 Million Yuan Net Loss in First Quarter of 2023 May 11, 2023 08:00 AM
Raw test results, delivered straight to your inbox, can spark confusion at best and panic at worst.
Close to 200 hospital heads have been detained in a monthslong anticorruption campaign aimed at helping Xi Jinping’s “common prosperity” drive.
Opinion: ObamaCare Turns Out to Be Affordable Only for the Healthy
Mariía Verza and Maddie Burakoff, Associated Press
Sean Fogler, For The Inquirer
The Code
Dr. John Campbell Sep 13, 2023 Nuremberg Code (1947) https://research.unc.edu/human-resear... https://encyclopedia.ushmm.org/conten... https://encyclopedia.ushmm.org/conten... Medical Case: US prosecutor details illegal experiments In case you want to support our community work use the following: https://www.justgiving.com/crowdfundi... https://www.buymeacoffee.com/awmedica...patreon:https://www.patreon.com/awmedicalvideos Link to our organization's website: https://buwanga.org/Donate: SENDWAVE/ WorldRemit / Wise transfer/Money Gram Mobile money number:+256785698803 Country: Uganda Registered name: Wefwafwa Andrew State: Eastern Uganda Address: Nkokojjeru Zip code:0000 Wallet Service provider:MTNE To contact Wefwafwa directly, wefandrew@gmail.com or WhatsApp+256756320736 Medical professionals on trial, after war for war crimes and crimes against humanity Including experiments on prisoners in the camp system. Doctors and nurses, participated in the killing of physically and mentally impaired Germans German doctors argued "Doctors Trial." 1946 Trials of War Criminals before the Nuremberg Military Tribunals under Control Council Law No. 10. Nuremberg October 1946 – April 1949 Their experiments differed little from those conducted before the war by German and American scientists. No international law or informal statement differentiated between legal and illegal human experimentation. “Permissible Medical Experiments.” Washington. U.S. Government Printing Office (n.d.), vol. 2., pp. 181-182. One The voluntary consent of the human subject is absolutely essential. This means that the person involved should have legal capacity to give consent; should be situated as to be able to exercise free power of choice, without the intervention of any element of force, fraud, deceit, duress, over-reaching, or other ulterior form of constraint or coercion, and should have sufficient knowledge and comprehension of the elements of the subject matter involved as to enable him to make an understanding and enlightened decision. Before the acceptance of an affirmative decision, subject should know the nature, duration, and purpose of the experiment; the method and means by which it is to be conducted; all inconveniences and hazards reasonably to be expected; and the effects upon his health or person which may possibly come from his participation in the experiment. The duty and responsibility for ascertaining the quality of the consent rests upon each individual who initiates, directs or engages in the experiment. It is a personal duty and responsibility which may not be delegated to another with impunity. Two The experiment should yield fruitful results for the good of society, unprocurable by other methods, and not random and unnecessary in nature. Three The experiment should be based on the results of animal experimentation, a knowledge of the natural history of the disease or other problem, the anticipated results will justify the performance of the experiment. Four The experiment should avoid all unnecessary physical and mental suffering and injury. Five No experiment should be conducted where there is an a priori reason to believe that death or disabling injury will occur; except, perhaps, in those experiments where the experimental physicians also serve as subjects. Six The degree of risk should never exceed, that determined by the humanitarian importance, of the problem to be solved by the experiment. Seven Proper preparations should be made, and adequate facilities provided, to protect the experimental subject against even remote possibilities of injury disability or death. Eight The experiment should be conducted only by scientifically qualified persons. The highest degree of skill and care should be required through all stages of the experiment Nine During the course of the experiment the human subject should be at liberty to bring the experiment to an end Ten During the course of the experiment the scientist in charge must be prepared to terminate the experiment at any stage, that continuation of the experiment is likely to result in injury, disability, or death to the experimental subject.
Serious adverse events
Dr. John Campbell Sep 11, 2023
What stimulated you to carry out this research in the first place, what got you interested in the topic? You refer to the Brighton Collaboration, what is this and how did this feed in to your thinking? Brighton Collaboration identified adverse events of special interest following covid vaccinations, what adverse events were identified? You conducted a secondary analysis of the placebo-controlled, phase III randomized clinical trials of Pfizer and Moderna mRNA COVID-19 vaccines in adults. Tell us a bit about these trials, is this sort of trial standard in testing new pharmaceuticals? What is a secondary analysis? What do you mean by excess risk? What excess risk did you discover? Pfizer vaccines excess risk of serious adverse events 10.1 per 10,000 Higher than placebo baseline of 17.6 per 10,000 Is it fair to say that this transposes into one serious adverse event per 990 vaccines? Moderna vaccines excess risk of serious adverse events 15.1 per 10,000 Higher than placebo baseline of 42.2 per 10,000 Is it fair to say that this transposes into one serious adverse event per 662 vaccines? Combined RNA covid vaccines excess risk of serious adverse events 12.5 per 10,000 Is it fair to say that this transposes into one serious adverse event per 800 vaccines? You also gave reanalysis data in terms of risk ratio. What is risk ratio? Combined, 1.43 Pfizer trial Exhibited, 36 % higher risk of serious adverse events in the vaccine group Risk ratio 1.36 Moderna trial Exhibited, 6 % higher risk of serious adverse events in the vaccine group Risk ratio 1.06 Combined Exhibited, 16 % higher risk of serious adverse events in the vaccine group Risk ratio 1.16 These risks of harm sound high to me, how does this level of risk compare to other vaccines and treatments? You suggest a formal harm-benefit analyses, what is this and how would this be done? What are participant level datasets, are these important. Did you have access to participant level datasets The original vaccine papers indicated high levels of efficacy in protecting against infection. What is the difference between relative and absolute risk? Were these results presented as relative or absolute risk of infection? Would it have been useful if the original vaccine trial papers had presented absolute risk as well as relative risk? FDA Now using near real time surveillance for vaccine safety. Is this near real time claim working, are we getting timely data? Is there a risk of false positives in the FDA data collection, or are false negatives an issue? Can the FDA safely ignore AESIs that are of minimal clinical significance? Is the FDA methodology confirming previously known AESIs, or is it missing some? From where is the FDA collecting data and are the data from all sources pooled to improve the power of the analysis? Is all data being collected from all 50 States? Is all FDA data open to independent peer review?
Dr. Joseph Fraiman, Serious adverse events of special interest following mRNA COVID-19 vaccination in randomized trials in adults Paper in Vaccine, 31 August 2022. https://pubmed.ncbi.nlm.nih.gov/36055...
BiotechSTORM™ novel coronavirus (2019-nCoV)/Monkeypox/Polio
FDA approves new Covid-19 booster shot as cases are on the rise
NBC News Sep 11, 2023 #Covid #Booster #Vaccine
The FDA has given the all clear for a new Covid-19 booster shot as cases are on the uptick. The new vaccines from Moderna and Pfizer could go into arms by the end of the week.
ADHD Drug Shortages Worsen as Makers Say Production Is Maxed Out
The Food and Drug Administration on Monday cleared updated boosters from Pfizer and Moderna for people six months and older.
Sad excess deaths
Dr. John Campbell Sep 8, 2023
Our world in data covid vaccination status https://ourworldindata.org/coronavirus
Office for health improvement https://app.powerbi.com/view?r=eyJrIj... https://www.ons.gov.uk/peoplepopulati...
Week ending 25 August 2023 (Week 34) England and Wales 10,086 deaths 203 mentioned novel coronavirus 2.0% of all deaths Of the 203 deaths 67.0% (136 deaths) recorded as underlying cause of death Deaths registered in the UK 11,522, (4.5% above five-year average)
Crushing worries: Treating generalized anxiety disorder
Healthy ejaculate is white. If it's yellowish or red or smells strange, this may indicate a disease. September 4, 20230
Innovative technology driven by artificial intelligence is enabling early detection and treatment of diabetes in India. August 31, 2023
Working from home has become established practice in Germany. The concept of coworking could be a boon for rural areas. August 29, 2023
August 25, 2023
August 24, 2023
August 29, 2023
New Covid variant 'Pirola' sparks alarm in many countries | WION Newspoint
WION Sep 5, 2023 #pirolavariant #covid19 #latestnews
An article published in the Yale Medicine Review on August 31 has noted the rise of Covid-19 infections in multiple countries, driven by a new Coronavirus variant called BA.2.86, which is informally being termed ‘Pirola’. #pirolavariant #covid19 #latestnews
A Mysterious Lab Is Shutting Down. It’s the End of an Era for Biosecurity.
Late-stage diagnoses have risen and a decline in deaths has stalled.
By Annie Gowen, Niko Kommenda and Saiyna Bashir
By Kevin Loria
By Andrew Jeong
By David Ovalle, Katie Shepherd and Laurie McGinley
As many as 9,000 Americans die each year after receiving the wrong prescription drugs or doses. Pharmacies are fighting a bill to shed light on the problem.
Prognosis A Vaccine That Repels Ticks Could Protect Beyond Lyme
In Wuhan, doctors knew the truth. They were told to keep quiet.
Opinion In Wuhan, doctors knew the truth. They were told to keep quiet.
By the Editorial Board |August 22, 2023 at 7:30 a.m. EDT
In January 2020, the system failed as the virus spread. This can be gleaned from documents and interviews conducted by Chinese journalists. They managed to capture a revelatory picture of the struggle by doctors and hospitals despite China’s strict limits on news reporting and its system of censorship. Gilles Demaneuf of the research group DRASTIC, which has been probing the origins of the virus, has compiled and translated these materials in a 193-page report he has shared with the World Health Organization’s Scientific Advisory Group for the Origins of Novel Pathogens. The report was made available to us. The findings are augmented by disclosures from U.S. Right to Know, a freedom-of-information group, and news accounts and congressional investigations in the United States.
https://www.washingtonpost.com/opinions/2023/08/22/wuhan-doctors-pandemic-china-coverup/
Natural immunity wins
Dr. John Campbell Aug 31, 2023
Natural immunity 27 times better Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Naturally Acquired Immunity versus Vaccine-induced Immunity, Reinfections versus Breakthrough Infections: A Retrospective Cohort Study https://academic.oup.com/cid/article/...
Background Waning of protection, conferred by 2 doses of the BNT162b2 vaccine, begins shortly after injection, becomes substantial within 4 months. We examined long-term protection of naturally acquired immunity, compared to vaccine-induced immunity. Group 1, N = 673,676 Vaccine not Infection Group SARS-CoV-2-naive individuals who received a 2-dose regimen of the BioNTech/Pfizer mRNA BNT162b2 vaccine. Group 2, N = 62,883 Infection not Vaccine Group Previously infected individuals who have not been vaccinated SARS-CoV-2-related outcomes June 1st to August 14th 2021 (Delta variant times) Infection, 13 times more infections in vaccinated group Symptomatic disease, 27 times more disease in vaccinated group Hospitalization, 8 in vaccinated group, 0 in infection group Death 0 / 0 Results When the first event (infection or vaccination) occurred during January and February of 2021. That’s 4 months up to 8 months Vaccinees not Infection Group, 13.06-fold increased risk for infection, compared to Infection not Vaccine Group Group 2, Infection not Vaccine Group, 13 times less likely to get infected with delta Group 2, Infection not Vaccine Group, 27 times less likely to get symptomatic infection. Group 2, Infection not Vaccine Group, 0 COVID-19-related hospitalizations Group 1, Vaccine not Infection Group, 8 COVID-19-related hospitalizations Allowing for more time since first event 6 to 17 months after first event Evidence of waning naturally acquired immunity was demonstrated Vaccine not Infection Group, 5.96-fold increased risk for infection Vaccine not Infection Group, 7.13-fold increased risk for symptomatic disease. Conclusions Naturally acquired immunity confers stronger protection against infection and symptomatic disease caused by the Delta variant of SARS-CoV-2, compared to the BNT162b2 2-dose vaccine-indued immunity. Cleveland Clinic https://www.medrxiv.org/content/10.11...
Health-care workers 1,359 unvaccinated, who had previously tested positive, non got infected The study authors concluded: “individuals who have had SARS-CoV-2 infection are unlikely to benefit from covid-19 vaccination.” Professor Marty Makary, Johns Hopkins School of Medicine and Bloomberg School of Public Health, editor-in-chief of Medpage Today https://www.washingtonpost.com/outloo...
It’s okay to have an incorrect scientific hypothesis. But when new data proves it wrong, you have to adapt. Unfortunately, many elected leaders and public health officials have held on far too long to the hypothesis that natural immunity offers unreliable protection against covid-19, a contention that is being rapidly debunked by science. Sixteen studies have demonstrated the power of acquired immunity That’s why it’s so frustrating that the Biden administration has repeatedly argued that immunity conferred by vaccines is preferable to immunity caused by natural infection, In my clinical experience, I have found patients to be extremely forgiving with evolving data if you are honest and transparent with them. The incorrect hypothesis that natural immunity is unreliable has resulted in the loss of thousands of American lives, avoidable vaccine complications, and damaged the credibility of public health officials. it would be good for our public health leaders to show humility by acknowledging that the hypothesis they repeatedly trumpeted was not only wrong, but it may be harmful. Public health officials changing their position on natural immunity, after so much hostility toward the idea, would go a long way in rebuilding the public trust.
New WHO chief scientist backs fact-finding mission to China to examine whether COVID accidentally leaked from Wuhan virus lab
BY CHRISTIAAN HETZNER August 21, 2023 at 8:43 AM EDT
https://fortune.com/2023/08/21/covid-lab-leak-china-who-chief-scientist-jeremy-farrar/
Covid Is Back. Is It Time to Pull Out Our Masks Again? Jessica Karl
The law was intended to protect patients from physicians who gave advice they knew to be false or misleading. But many doctors feared the law was too vague.
CDC, increased infection risk in vaccinated
Dr. John Campbell Aug 29, 2023
BA.2.86 may be more capable of causing infection in people who have previously had COVID-19 or who have received COVID-19 vaccines. New variant and vaccine escape Risk Assessment Summary for SARS CoV-2 Sublineage BA.2.86 https://www.cdc.gov/respiratory-virus...
https://www.medscape.com/s/viewarticl...
BA.2.86, detected in Denmark and Israel At least two cases in the United States. UK Health Security Agency, UK case, no recent travel history Cases not epidemiologically linked (therefore already widespread) Multiple genetic differences from previous SARS-CoV-2 Existing tests appear to be effective BA.2.86 may be more capable of causing infection in people who have previously had COVID-19 or who have received COVID-19 vaccines. ? stimulation of T suppressor (regulatory) cells ? stimulation of IgG4
https://www.science.org/doi/10.1126/s...
No evidence BA.2.86 causing more severe illness. Updated vaccines will be available as early as mid-September What can you do to protect yourself and others as we learn more? Get your COVID-19 vaccines, as recommended https://www.cdc.gov/coronavirus/2019-...
COVID-19 Vaccines Are Safe, Effective, and Free Everyone 6 months and older should get an updated COVID-19 vaccine. BA.2.86 https://www.nature.com/articles/d4158...
Many spike protein changes (explain vaccine immune escape) Could out compete common EG.5 (Latest COVID-19 booster vaccines are based on XBB.1.5) Jesse Bloom, viral evolutionary biologist, Fred Hutchinson Cancer Center Seattle, Washington “I don’t think anybody needs to be alarmed by this,” “The most likely scenario is that this variant fizzles out, and in a month nobody other than people like me even remember that it existed.” Even if BA.2.86 does becomes widespread, and proves adept at dodging neutralizing antibodies, which seems likely, on the basis of its set of spike mutations, other forms of immunity will probably stop most people from getting seriously ill if they are infected
Rocky Mountain spotted fever is on the rise in parts of Mexico and the United States. Climate change and dogs could be crucial to the fight against the tick-borne scourge.By Lena Sun | Photos by Michael Robinson Chávez
By The Editorial Board | Review & Outlook
Comirnaty: EMA recommends approval of adapted COVID-19 vaccine targeting Omicron XBB.1.5
30/08/2023
EMA’s human medicines committee (CHMP) has recommended authorising an adapted Comirnaty vaccine targeting the Omicron XBB.1.5 subvariant.
The vaccine – known as Comirnaty Omicron XBB.1.5 – is to be used for preventing COVID-19 in adults and children from 6 months of age.
In line with previous recommendations by EMA and the European Centre for Disease Prevention and Control (ECDC), adults and children from 5 years of age who require vaccination should have a single dose, irrespective of their COVID-19 vaccination history.
US Health Officials Call for Moving Marijuana to Lower-Risk US Drug Category
COVID cases are rising, but should we start wearing masks again?
CBS Boston Aug 24, 2023
With the recent rise in COVID-19 cases and hospitalizations, many are wondering whether it's time to start masking up again.
By Matthew Hennessey | Commentary
Lyme Disease Has Exploded, and a New Vaccine Is (Almost) Here
By Kristen V Brown and Nacha Cattan
How Often Are People Getting Stuck With Long Covid?
By Kristen V Brown August 27, 2023 at 6:00 AM EDT
By Mikkael A. Sekeres | Commentary
Wealthy People Are Getting Full-Body Scans. Early Detection or Unnecessary?
With coronavirus transmission on the rise, the FDA said this year’s updated version of the COVID-19 vaccine is likely to come out by the middle of next month.
Lyme Disease Has Exploded, and a New Vaccine Is (Almost) Here
Myocarditis, don't bother to report
Dr. John Campbell Aug 23, 2023
TGA to stop reporting myocarditis To donate to the work of campbellteaching around the world, https://www.paypal.com/donate/?hosted...
Myocarditis is reported in around 2 in every 100,000 of those who receive Spikevax (Moderna). As reporting rates of myocarditis and pericarditis following vaccination are very stable, we will not include this section in future COVID-19 vaccine safety reports. However, we continue to monitor and review these adverse effects and will communicate any updated safety advice if needed.
https://www.tga.gov.au/news/covid-19-... https://www.outkick.com/silent-killer...
Primary course recommendations COVID-19 vaccination is recommended for all people aged 5 years or older to protect against COVID-19. For most people, a primary vaccination course consists of 2 doses. Adverse reactions, TGA data One adverse event report per 490 doses given, 0.2039% In Western Australia
https://www.health.wa.gov.au/~/media/...
0.241% 10,428 adverse events (97%) occurred after a COVID-19 vaccine 21 times more common than ‘conventional’ vaccines Swiss data Myocardial Injury after COVID-19 mRNA-1273 Booster Vaccination
https://onlinelibrary.wiley.com/doi/e... mRNA-1273 vaccine-associated myocardial injury was adjudicated in 22 participants (2.8%). (N = 777 per group) One in 35 recipients (2.8%) had vaccine-associated myocardial injury Matched controls, elevated high-sensitivity cardiac troponin T concentration Significantly higher in post vaccination group p less than 0.001 Thai study Cardiovascular Manifestation of the BNT162b2 mRNA COVID-19 Vaccine in Adolescents https://www.ncbi.nlm.nih.gov/pmc/arti...
After BNT162b2, 2nd dose, Thai adolescents, aged 13–18 years, n = 314 Seven participants (2.33%) exhibited at least one elevated cardiac biomarker Myopericarditis was confirmed in one patient after vaccination. Two patients had suspected pericarditis Four patients had suspected subclinical myocarditis Hence, adolescents receiving mRNA vaccines should be monitored for cardiovascular side effects. Israeli study A prospective study on myocardial injury after BNT162b2 mRNA COVID-19 fourth dose vaccination in healthy persons https://pubmed.ncbi.nlm.nih.gov/36097...
Incidence of myocardial injury after fourth dose BNT162b2 mRNA vaccine (Pfizer-BioNTech) N = 324 Reported vaccine-related adverse reactions Chest pain in 12 (3.7%) Palpitations in 7 (2.16%) Vaccine-related myocardial injury in two (0.62%) https://www.gov.uk/government/publica...
Post-COVID-19 vaccination As of 23 November 2022, following Pfizer/BioNTech 851 reports of myocarditis and 579 reports of pericarditis Total of 1,430 Following Moderna vaccine 251 reports of myocarditis 149 reports of pericarditis Total of 1,530 As of 23 November 2022, myocarditis following monovalent Pfizer/BioNTech was 10 reports per million doses; If there is a suspicion of myocarditis or pericarditis, initial investigations should be: 12 lead electrocardiogram (ECG) inflammatory blood markers (C-reactive protein (CRP), full blood count (FBC) and erythrocyte sedimentation rate (ESR) Troponin If there is no evidence of ongoing myocarditis, vaccination may be considered with the Pfizer/BioNTech (Cominarty) vaccine from 12 weeks after their last dose if further doses are due. If the individual feels well after receiving their COVID-19 vaccination, then there is no need to pre-emptively restrict physical activity post vaccination and individuals can continue with their pre-existing level of physical activity.
This winter will be the first time vaccines for RSV, flu and COVID-19 will be available
KSBY News Aug 18, 2023
This winter will be the first time vaccines for RSV, flu and COVID-19 will be available
Doctors expect tens of thousands fewer infant hospitalizations because of new RSV tools.
In Wuhan, doctors knew the truth. They were told to keep quiet.
Study: Kids who’ve been assaulted more likely to develop mental illness
By Erin Blakemore
By Aara'L Yarber
08.21.2023 Vaccines
https://www.abrysvo.com/older-adults
The move is expected to cut prices in a few years for some patients but faces litigation from the drugmakers and heavy criticism from Republican lawmakers.
COVID hospitalizations on the rise: Do you need another booster?
TODAY Aug 18, 2023 #booster #covid #vaccine
COVID cases and hospitalizations are on the rise with some of the biggest spikes in Mississippi, Alabama and Louisiana. NBC medical contributor Dr. Natalie Azar joins TODAY to weigh in on safety precautions, including getting another booster.
Long covid has derailed my life. Make no mistake: It could yours, too. Opinion
Covid gave me 2 options: Give in to alcohol addiction, or choose life Opinion
By Emily Laber-Warren
By Prayag Gordy and Peter Jamison
The newly constituted all-male court reversed itself from a ruling earlier this year.
In a study, the medicine eased symptoms of the heart condition, which can cause fatigue and shortness of breath and lead to hospitalizations and deaths.
Moderna paid 400 million to NIH
Dr. John Campbell Aug 18, 2023
Senate Health, Labor, and Pensions Committee hearing https://www.c-span.org/video/?c506318... Senator Rand Paul Moderna CEO Stéphane Bancel, Moderna paid NIH $400,000,000 Making money from the vaccine while dictating government policy on how many times the vaccine is used. ‘Thank you for the question Senator’ 16 to 24 years vaccine increased myocarditis, Especially after the 2nd dose "I spoke with your president just last week and he readily acknowledged, in private, that yes there is an increased risk of myocarditis. The fact that you can't say it in public is quite disturbing." CDC Covid, vaccine, myocarditis, vaccine, vaccine CDC/FDA latest guidelines https://twitter.com/FDAHealthEquity/s... https://www.cdc.gov/vaccines/covid-19... 6 months to 5 years 6 years and older https://www.cdc.gov/coronavirus/2019-
Covid-19 cases on the rise and a new booster is in the pipeline
NBC News Aug 17, 2023 #Covid #Health #Booster
Covid-19 hospitalizations jumped more than 14 percent across the country in the most recent week, signaling a Covid resurgence. NBC News’ Anne Thompson has more details on the new vaccine boosters and when they may become available.